Polynucleotides

Polynucleotides are an advanced, non-invasive treatment in regenerative and pro-aging aesthetics, designed to improve skin quality, hydration, and elasticity at a cellular level. This innovative injectable treatment works by stimulating fibroblast activity, naturally increasing collagen and elastin production to restore healthier, more radiant skin.

Polynucleotides are particularly effective for:

  • Reducing fine lines and wrinkles

  • Improving skin hydration and glow

  • Smoothing skin texture and tone

  • Minimising dark under-eye circles, puffiness, and hollowness

  • Protecting skin from free radical damage and environmental stress

This treatment is ideal for delicate areas such as the under-eyes, face, neck, and décolletage, making it a versatile solution for patients seeking natural skin rejuvenation without downtime.

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Polynucleotides treatment features

Treatment results

Improvement in dark circles Glowing hydrated skin

Treatment time

Approx 15-20 minutes

Recovery time

1-2 days

Treatment longevity

Results should last 6-9 months.

Frequently asked questions about Polynucleotides

Polynucleotide injections are well-tolerated and minimally uncomfortable for most patients. You may feel a light pinching or mild stinging sensation during the injection, particularly in delicate areas such as the under-eyes or décolletage, but any discomfort is brief and manageable. Thanks to their gentle formulation, polynucleotide skin treatments are ideal for sensitive skin and areas prone to bruising or swelling. There is minimal downtime, with most patients returning to normal activities the same day.

Topical anaesthetic is available if necessary.

The procedure itself takes no more than 10 minutes. However a thorough medical consultation is required prior to this to ensure this is the right treatment for you.

You can expect to see visible improvements in skin hydration, texture, and radiance within 7 to 10 days after your first polynucleotide treatment. However, the full benefits—including firmer, smoother, and more youthful-looking skin—develop gradually over 3 to 6 weeks as your skin produces more collagen and elastin.

For the best and most long-lasting results, we recommend a course of 2-3 polynucleotide treatments, spaced 2–4 weeks apart. Continued improvement is seen in the weeks following your final session as the skin continues its natural regeneration process.

Results from polynucleotide skin treatments typically last 6 to 9 months, depending on your skin type, age, lifestyle, and skincare routine. As collagen and elastin production is gradually stimulated, the skin becomes firmer, more hydrated, and visibly more radiant over time. Many patients choose to have maintenance treatments every 6 months to sustain and enhance their results.

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